Welcome to the Sakellariou Group on NMR and MRI

Patents:

International Patents #198341445.8 and (US6184683): "Method to Improve Resolution of Two-Dimensional Heteronuclear Correlation Spectra in Solid-State NMR" (US Patent # 6,184,683).
International Patent (WO 2006/023208) and (US 20090261826): "Low Field Magnetic Resonance Imaging" (check the WIPO).
International Patents (WO 2007/020537) and (WO 2007/003218): "Apparatus for high resolution NMR spectroscopy and/or imaging with an improved filling factor and rf amplitude amplitude" (check the WIPO).
US Patent #6,674,282: "Method and Apparatus for High Resolution Ex-Situ NMR Spectroscopy".
International Patent and (WO 2006/028588) "Nuclear Magnetic Resonance Detection in Inhomogeneous Magnetic Fields" (check the WIPO).
International Patents (WO 2003/016951) and (WO 2002/082116) "Method and Apparatus for High Resolution Ex-Situ NMR Spectroscopy" (check the WIPO).
International Patent Application (WO 2011/023910) "Cylindrical Permanent Magnet Device With an Induced Magnetic Field Having a Predetermined Orientation, and Production Method" (check the WIPO).
International Patent Application (WO/2011/023911) "Cylindrical Permanent Magnet Device Generating a Controlled Magnetic Field at a Distance from the Surface thereof" (check the WIPO).
International Patent Application (WO/2011/023912) "Assembly of Magnetised Coaxial Structures Inducing a Longitudinal Homogeneous Field in the Centre thereof" (check the WIPO).
International Patent Application (WO/2011/023913) "Magnetized Structure Inducing a Homogeneous Field, in the Centre thereof, with a Pre-determined Orientation" (check the WIPO).
International Patent Application (WO/2014/128399) "Method and device for magnetic field correction for an NMR machine" (check the WIPO).
International Patent Application (WO/2014/155312) "NMR probe comprising a coil including two helical windingshaving turns of different opposing angles of between 0 and 90 degrees relative to the axis thereof" (check the WIPO).

Peer reviewed articles:

(84) C-Y. Chou, M. Abdesselem, C. Bouzigues, M. Chu, T-H. Huang, F. Ferrage, T.Gacoin, A. Alexandrou and D. SAKELLARIOU, "Ultra-wide range field-dependent measurements of the relaxivity of Gd_1-xEu_xVO₄ nanoparticle contrast agents using a mechanical sample-shuttling relaxometer", Sci. Rep., in press (2017). link

(83) P. Judeinstein, F. Ferdeghini, R. Oliveira-Silva, J-M. Zanotti and D. SAKELLARIOU, "Low-field single-sided NMR for one-shot 1D-mapping: Application to membranes", J. Magn. Reson., in press (2017). link

(82) S. F. Cousin, C. Charlier, P. Kaderavek, T. Marquardsen, J.-M. Tyburn, P.-A. Bovier, S. Ulzega, T. Speck, D. Wilhelm, F. Engelke, W. Maas, D. Sakellariou, G. Bodenhausen, P. Pelupessy, F. Ferrage, "High-Resolution Two-Field Nuclear Magnetic Resonance Spectroscopy", PCCP, 18, 33187 (2016). link

(81) C-Y. Chou, M. Chu, C-F. Chang, T. Yu, T-h. Huang and D. Sakellariou, "High Sensitivity High-Resolution Full Range Relaxometry Using a Fast Mechanical Sample Shuttling Device and a Cryo-probe", J. Biomol. NMR, (2016). link

(80) J. Lehmann-Horn, J-F. Jacquinot, J-C. Ginefri, C. Bonhomme and D. Sakellariou, "Monolithic MACS micro resonators", J. Magn. Reson., 271, 46 (2016).link

(79) Y. Gossuin, Z. Serhan, L. Sandiford, D. Henrard, T. Marquardsen, R. T. M. de Rosales, D. Sakellariou and F. Ferrage, "Sample Shuttling Relaxometry of Contrast Agents: NMRD Profiles above 1 T with a Single Device", Appl. Magn. Reson., 47, 237 (2016). link

(78) J-M. Zanotti, P. Judeinstein, S. Dalla-Bernardina, G. Creff, J-B. Brubach, P. Roy, M. Bonetti, J. Ollivier, D. Sakellariou and M-C. Bellissent-Funel, "Competing coexisting phases in 2D water", Sci. Rep., 6, 25938 (2016). link

(77) C. Chou, F. Ferrage, G. Aubert and D. Sakellariou, "Simple method for the generation of multiple homogeneous field volumes inside the bore of superconducting magnets", Sci. Rep., 5, 12200 (2015). link

(76) A. Wong, X. Li, L. Molin, F. Solari, B. Elena-Herrmann and D. Sakellariou, "μHigh Resolution-Magic-Angle Spinning NMR Spectroscopy for Metabolic Phenotyping of Caenorhabditis elegans", Anal. Chem. , 86, 6064 (2014). link

(75) C. Charlier, S. Khan, T. Marquardsen, P. Pelupessy, V. Reiss, D. Sakellariou, G. Bodenhausen, F. Engelke and F. Ferrage, "Nanosecond timescale motions in proteins revealed by high-resolution NMR relaxometry", J. Am. Chem. Soc., 135, 18665 (2013). link

(74) J. Alonso, A. Soleilhavoup, A. Wong, A. Guiga and D. Sakellariou, "Double Helix Dipole Design Applied to Magnetic Resonance: A Novel NMR Coil", J. Magn. Reson., 235, 32 (2013). link

(73) X. Li, C. Hugon, J. Polesel-Maris, V. Martinez and D. Sakellariou, "Simple procedure for the fabrication of flexible NMR shim coils", C. R. Chimie, 16, 967 (2013). link

(72) K. Panesar, C. Hugon, G. Aubert, P. Judenstein, J.-M. Zanotti and D. Sakellariou "Measurement of self-diffusion in thin samples using a novel one-sided NMR magnet", Micropor. Mesopor. Mater., 178, 79 (2013). link

(71) C. Hugon, X. Li, G. Aubert and D. Sakellariou "Generalized shim and gradient generation: Application to the magic angle field spinning case", Micropor. Mesopor. Mater., 178, 31 (2013). link

(70) A. Wong, X. Li and D. Sakellariou "Refined Magic-Angle Coil Spinning Resonator for Nanoliter MAS NMR Spectroscopy: Enhanced Spectral Resolution", Anal. Chem., 85, 2021 (2013). link

(69) G. Aubert, J-F. Jacquinot and D. Sakellariou "Eddy current effects in plain and hollow cylinders spinning inside homogeneous magnetic fields: application to magnetic resonance", J. Chem. Phys., 137, 154201 (2012). link

(68) V. Badilita, B. Fassbender, K. Kratt, A. Wong, C. Bonhomme, D. Sakellariou, J. G. Korvink and U. Wallrabe, "Microfabricated inserts for magic angle coil spinning (MACS) wireless NMR spectroscopy", PLoS ONE, 7, e42848 (2012). link

(67) D. Sakellariou, "L'Instrumentation en Resonance Magnetique Nucleaire : une affaire de haute sensibilite", L'Actualite Chimique, 364-365, 117 (2012). link

(66) A. Wong, B. Jimenez, X. Li, E. Holmes, J. Nicholson, J. Lindon and D. Sakellariou, "Evaluation of High Resolution Magic-Angle Coil Spinning NMR Spectroscopy for Metabolic Profiling of Nanoliter Tissue Biopsies", Analytical Chemistry, 84, 3843 (2012). link

(65) C. Hugon, G. Aubert and D. Sakellariou, "An expansion of the field modulus suitable for the description of strong field gradients. Application to single-sided magnet design, field mapping and STRAFI.", J. Magn. Reson., 214, 124 (2012). link

(64) A. Wong and D. Sakellariou, "Sensitivity Enhanced Natural Abundance Silicon-29 Magnetic Resonance Imaging", Chem. Phys. Chem., 12, 3529 (2011). link

(63) V. Badilita, B. Fassbender, O. Gruschke, K. Kratt, R. Meier, D. Sakellariou, J. G. Korvink and U. Wallrabe, "Inductivelly Coupled Wirebonded Microcoils for wireless on-chip NMR", Transducers, 2798, (2011). link

(62) J-F. Jacquinot and D. Sakellariou, "NMR Signal Detection using Inductive Coupling: Applications to Rotating Micro-coils", Concepts Magn. Reson. A, 38, 33 (2011). link

(61) A. Wong, P. M. Aguiar, T. Charpentier and D. Sakellariou, "A low-cost strategy for 43Ca solid-state NMR spectroscopy", Chem. Science, 2, 815 (2011). link

(60) P. M. Aguiar, J-F. Jacquinot and D. Sakellariou, "A convenient, high-sensitivity approach to multiple-resonance NMR at nanolitre volume with inductively-coupled micro-coils", Chem. Comm., 47, 2119 (2011). link

(59) C. Hugon, G. Aubert and D. Sakellariou, "A Systematic Approach to the Design, Fabrication and Testing of Permanent Magnets Applied to Single-Sided NMR", AIP Proceedings of MRPM10, 1330, 105 (2011). link

(58) D. Pagliero, W. Dong, D. Sakellariou and C. A. Meriles, "Time-resolved, optically detected NMR of fluids at high magnetic field", J. Chem. Phys., 133, 154505 (2010). link

(57) D. Sakellariou, C. Hugon, A. Guiga, G. Aubert, S. Cazaux and P. Hardy, "Permanent Magnet Assembly producing a Strong Tilted Homogeneous Magnetic Field: Towards Magic Angle Field Spinning NMR and MRI", Magn. Reson. Chem., 48, 903 (2010). link

(56) A. Wong and D. Sakellariou, "Contrast STRAFI-MAS Imaging", J. Magn. Reson., 206, 264 (2010). link

(55) A. Sinanna, P. M. Aguiar, F. d'Amico, S. Bermond, P. Bredy, A. Donati, C. Hugon, H. Lannou, D. Sakellariou, T. Schild, and P. Tixador, "Field Stabilization of the Iseult/Inumac Magnet Operating in Driven Mode", IEEE Trans. Appl. Supercond., 20, 790 (2010). link

(54) A. Wong and D. Sakellariou, "Two- and three-dimentional multinuclear stray-field imaging of rotating samples with Magic-Angle Spinning (STRAFI-MAS): From bio to inorganic materials", J. Magn. Reson. Imag., 32, 418 (2010). link

(53) C. Hugon, F. d'Amico, G. Aubert, and D. Sakellariou, "Design of arbitrarily homogeneous permanent magnet systems for NMR and MRI: theory and experimental developments of a simple portable magnets", J. Magn. Reson., 205, 75 (2010). link

(52) A. K. L. Yuen, O. Lafon, T. Charpentier, M. Roy, F. Brunet, P. Berthault, D. Sakellariou, B. Robert, S. Rimsky, F. Pillon, J-C. Cintrat and B. Rousseau, "Measurement of Long-Range Interatomic Distances by Solid-State Tritium-NMR Spectroscopy", J. Am. Chem. Soc., 132, 1734 (2010). link

(51) C. Hugon, P. Aguiar, G. Aubert, D. Sakellariou, "Design, Fabrication and Evaluation of a Low-Cost Homogeneous Portable Permanent Magnet for NMR and MRI", Comptes Rendus Chimie, 13, 388 (2010). link

(50) A. Wong, P. Aguiar, D. Sakellariou, "Slow magic-angle coil spinning: A high sensitivity and high-resolution NMR strategy for microscopic biological specimens", Magn. Reson. Med., 63, 269 (2010). link

(49) C. Hugon, J-F. Jacquinot and D. Sakellariou, "Measurements of magnetic field stability in inhomogeneous magnetic fields at low temperature", J. Magn. Reson., 202, 1 (2010). link

(48) A. Sinanna, S. Bermond, A. Donati, P. Gros, C. Hugon, J-F. Jacquinot, M. Lakrimi, D. Sakellariou, T. Schild, P. Tixador, "Field Stabilization of an MRI Magnet Operating in Driven Mode", IEEE Trans. on Applied Superconductivity, 19, 2301, (2009). link

(47) P. M. Aguiar, J-F. Jacquinot, and D. Sakellariou, "Experimental and numerical examination of eddy (Foucault) currents in rotating micro-coils: Generation of heat and its impact on sample temperature.", J. Magn. Reson., 200, 6 (2009). link

(46) V. Demas, J. M. Franck, L. S. Bouchard, D. Sakellariou, C. A. Meriles, R. Martin, P. J. Prado, A. Bussandri, J. A. Reimer and A. Pines, "Ex-situ magnetic resonance volume imaging", Chem. Phys. Lett., 467, 398 (2009). link

(45) J. A. Tang, L. O'Dell, P. M. Aguiar, B. E. G. Lucier, D. Sakellariou and R. W. Schurko, "Application of Static Microcoils for Solid-State Wideline NMR Spectroscopy of Quadrupolar Nuclei ", Chem. Phys. Lett., 466, 227 (2008). link

(44) J-F. Jacquinot and D. Sakellariou, "Microdetecteurs rotatifs en resonance magnetique nucleaire", Techniques de l'ingenieur, IN85, Sept (2008). link
(43) T. Charpentier, D. Sakellariou, J. Virlet, F. S. Dzheparov and J-F. Jacquinot, "Nuclear spin dynamics using time-dependent projection operators: Application to the saturation of dipolar order in slowly rotating samples", J. Chem. Phys., 127, 224506 (2007). link

(42) D. Sakellariou and T. Charpentier, "Shift anisotropy Tensors in Amorphous Natural Abundance Solids: high-resolution ²⁹Si CSA Distributions under very slow sample rotation", Appl. Magn. Reson., 32, 583 (2007). link

(41) D. Bregiroux, F. Audubert, T. Charpentier, D. Sakellariou and D. Bernache-Assollant, "Solid-state synthesis of monazite-type compounds LnPO₄ (Ln=La to Gd)", Solid State Sciences, 9, 432 (2007).link.

(40) D. Sakellariou, G. Le Goff and J.-F. Jacquinot, "High-resolution, high-sensitivity NMR of nanolitre anisotropic samples by coil spinning", Nature, 447, 694 (2007). (link).
See what has written on the subject here.
Check also what has written on the subject here.
Read the article of entitled "Snapshots from the NMR frontier", where our work is cited.

(39) R. C. Jachmann, D. R. Trease, L.-S. Bouchard, D. Sakellariou, R. W. Martin, R. D. Schlueter, T. F. Budinger and A. Pines, "Multipole shimming of permanent magnets using harmonic corrector rings", Rev. Sci. Instrum., 78, 035115 (2007). (link)

(38) C. A. Meriles, D. Sakellariou and A. H. Trabesinger, "Theory of MRI in the presence of zero to low magnetic fields and tensor imaging field gradients", J. Magn. Reson., 182, 106 (2006). (link)

(37) D. Topgaard and D. Sakellariou, "Diffusion damping during adiabatic z-rotation pulses for NMR spectroscopy in inhomogeneous fields", J. Chem. Phys., 125, 044503 (2006). (link)

(36) V. Demas, C. Meriles, D. Sakellariou, S. Han, J. Reimer and A. Pines, "Toward Ex Situ Phase-Encoded Spectroscopic Imaging", Conc. Magn. Reson. B, 29, 137 (2006). (link)

(35) R. W. Martin, R. C. Jachmann, D. Sakellariou, U. G. Nielsen and A. Pines, "High-Resolution Nuclear Magnetic Resonance Spectroscopy of Biological Tissues Using Projected Magic Angle Spinning", Magn. Reson. Med., 54, 253 (2005). (link)

(34) D. Topgaard, D. Sakellariou and A. Pines, "NMR spectroscopy in inhomogeneous B₀ and B₁ fields with non-linear correlation", J. Magn. Reson., 175, 1 (2005). (link)

(33) D. Sakellariou, J. -F. Jacquinot and T. Charpentier, "2D correlation spectra of isotropic and anisotropic ²⁹Si chemical shifts in crystalline and amorphous natural abundance materials under very slow sample rotation", Chem. Phys. Lett., 411, 171 (2005). (link)
This paper shows how the study of radioactive materials can be made safer. Click here (in french) !

(32) D. Sakellariou, C. A. Meriles, R. W. Martin and A. Pines, "NMR in rotating magnetic fields: magic-angle field spinning", Magn. Reson. Imag., 23, 295 (2005). (link)

(31) C. A. Meriles, D. Sakellariou, A. Trabesinger, V. Demas and A. Pines, "Zero- to low-field MRI with averaging of concomitant gradient fields", Proc. Nat. Acad. Sci., 102, 1842 (2005). (link)

(30) D. Topgaard, R. W. Martin, D. Sakellariou, C. A. Meriles and A. Pines, "Shim pulses for NMR spectroscopy and imaging", Proc. Nat. Acad. Sci., 101, 17576 (2004). (link)

(29) G. H. J. Park, R. W. Martin, D. Sakellariou, A. Pines, A. G. Sahkhatuni, A. A. Sahkhatuni and H. A. Panosyan, "Variable angle spinning (VAS) NMR study of solvent effects in liquid crystalline solutions of 13C-iodomethane", Chem. Phys. Lett., 399, 196 (2004). (link)

(28) V. Demas, D. Sakellariou, C. A. Meriles, S. Han, J. Reimer and A. Pines, "Three-dimensional phase-encoded chemical shift MRI in the presence of inhomogeneous fields", Proc Nat. Acad. Sci., 101, 8845 (2004). (link)

(27) D. Sakellariou, C. A. Meriles and A. Pines, "Advances in ex-situ Nuclear Magnetic Resonance" , C. R. Physique, 5, 337 (2004). (link)

(26) C. A. Meriles, D. Sakellariou, A. Moule, M. Goldman, T. Budinger and A. Pines, "High-resolution NMR of static samples by rotation of the magnetic field" , J. Magn. Reson., 169, 13 (2004). (link)

(25) D. Sakellariou, C. A. Meriles, R. W. Martin and A. Pines, "High-Resolution NMR of Anisotropic Samples with Spinning Away from the Magic Angle", Chem. Phys. Lett., 377, 333 (2003). (link)

(24) C. A. Meriles, D. Sakellariou and A. Pines, "Broadband Phase Modulation by Adiabatic Pulses", J. Magn. Reson., 164, 177 (2003). (link)

(23) A. Lesage, D. Sakellariou, S. Hediger, B. Elena, P. Charmont, S. Steuernagel and L. Emsley, "Experimental aspects of proton NMR spectroscopy in solids using phase-modulated homonuclear dipolar decoupling", J. Magn. Reson., 163, 105 (2003). (link)

(22) L. Duma, S. Hediger, A. Lesage, D. Sakellariou and L. Emsley, "Carbon-13 Lineshapes in Solid-State NMR of Labeled Compounds Effects of Coherent CSA-Dipolar Cross Correlation", J. Magn. Reson., 162, 90 (2003). (link)

(21) D. Sakellariou, S. P. Brown, A. Lesage, S. Hediger, M. Bardet, C. A. Meriles, A. Pines and L. Emsley, "High-Resolution NMR Spectra of Disordered Solids", J. Am. Chem. Soc., 125, 4376 (2003). (link).
Check what has to say about this paper here.
This paper made it to the Highlights in Chemistry of C&EN for 2003. Check the cover story here (under Structure)

(20) G. De Paepe, D. Sakellariou, P. Hodgkinson, S. Hediger and L. Emsley, "Heteronuclear decoupling in solid state NMR using continuous phase modulation", Chem. Phys. Lett. 368, 511 (2003). (link)

(19) M. Marjanska, R. H. Havlin and D. Sakellariou, "Coherent averaging and correlation of anisotropic spin interactions in oriented molecules", chapter in NMR of Ordered Liquids, edited by E. E. Burnell and C. A. deLange, Kluner Scientific (2002). (link). Buy this book here

(18) S. Wi, J. Logan, D. Sakellariou, J. Walls and A. Pines, "Rotary Resonance Recouplings of Half-Integer Quadrupolar Nuclei in Solid-State Nuclear Magnetic Resonance Spectroscopy", J. Chem. Phys. 117, 7024 (2002). (link)

(17) D. Sakellariou, C. A. Meriles, A. Moulé and A. Pines, "Variable Rotation Composite Pulses for High Resolution Nuclear Magnetic Resonance Using Inhomogeneous Magnetic and Radio-Frequency Fields", Chem. Phys. Lett. 363, 25 (2002). (link)

(16) H. Heise, D. Sakellariou, C. A. Meriles, A. Moulé and A. Pines, "Two-Dimensional High-Resolution NMR Spectra in Matched B₀ and B₁ Field Gradients", J. Magn. Reson. 156, 146 (2002). (link)

(15) C. A. Meriles, D. Sakellariou and A. Pines, "Resolved magic-angle spinning of anisotropic samples in Inhomogeneous Fields", Chem. Phys. Lett. 358, 391 (2002). (link)

(14) D. J. Walls, M. Marjanska, D. Sakellariou, F. Castiglione and A. Pines, "Selective excitation in dipole coupled systems", Chem. Phys. Lett. 357, 241 (2002). (link)

(13) P. Charmont, D. Sakellariou, D. and L. Emsley, "Sample Restriction Using Radiofrequency Field Selective Pulses in High-Resolution Solid-State NMR", J. Magn. Reson. 154, 136 (2002). (link)

(12) D. Sakellariou and L. Emsley, "Through-bond experiments in solids", The Encyclopedia of NMR 9, 196 (2002). (link)

(11) A. Lesage, L. Duma, D. Sakellariou, and L. Emsley, "Improved Resolution in Proton NMR Spectroscopy of powdered solids", J. Am. Chem. Soc. 123, 5747 (2001). (link)

(10) C. A. Meriles, D. Sakellariou, H. Heise, A. Moulé and A. Pines, "Approach to High-Resolution Ex-Situ NMR Spectroscopy", Science 293, 82 (2001). (link)
Check what has to say about this paper here.
Look also at the LBNL report here.

(9) D. Sakellariou, A. Lesage and L. Emsley, "Proton-proton constraints in powdered solids from ¹H-¹H-¹H and ¹H-¹H-¹³C Three-dimensional NMR Chemical Shift Correlation Spectroscopy", J. Am.Chem. Soc. 123, 5604 (2001). (link)

(8) D. Sakellariou, A. Lesage and L. Emsley, "Spectral Editing in Solid-State NMR using Scalar Multiple Quantum Filters", J. Magn. Reson. 151, 40 (2001). (link)

(7) Z. Yao, H.-T. Kwak, D. Sakellariou, L. Emsley, P. J. Grandinetti, "Sensitivity Enhancement of the Central Transition NMR Signal of Quadrupolar Nuclei under Magic-Angle Spinning", Chem. Phys. Lett. 327, 85 (2000). (link)

(6) P. Hodgkinson, D. Sakellariou and L. Emsley, "Simulation of Extended Periodic Systems of Nuclear Spins", Chem. Phys. Lett. 326, 515 (2000). (link)

(5) D. Sakellariou, A. Lesage, P. Hodgkinson and L. Emsley, "Homonuclear Dipolar Decoupling in Solid-State NMR Using Continuous Phase Modulation", Chem. Phys. Lett. 319, 253 (2000). (link)

(4) D. Sakellariou, P. Hodgkinson, S. Hediger and L. Emsley, "Experimental Observation of Periodic Quasi Equilibria in Solid-State NMR", Chem. Phys. Lett. 308, 381 (1999). (link)

(3) A. Lesage, D. Sakellariou, L. Emsley and S. Steuernagel, "A New Carbon-Proton Chemical Shift Correlation Experiment for Solid-State NMR", Bruker Report 147, 7, (1999).

(2) A. Lesage, D. Sakellariou, S. Steurnagel and L. Emsley, "Carbon-Proton Chemical Shift Correlation in Solid-State NMR by Through-Bond Multiple-Quantum Spectroscopy", J. Am. Chem. Soc. 120, 13194 (1998). (link)

(1) D. Sakellariou, P. Hodgkinson and L. Emsley, "Quasi Equilibria in Solid-State NMR", Chem. Phys. Lett. 293, 110 (1998). (link)

The Sakellariou group on Magnetic Resonance: Publications

Patents:

Peer reviewed articles: